Description

4-(Hydroxy)Piperidine-1-Carboxamidine is a versatile and highly functionalized piperidine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a hydroxy group and a carboxamidine moiety, makes it a valuable precursor for constructing complex molecules with specific biological activity. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, including potential kinase inhibitors and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of new pesticides and herbicides, leveraging its piperidine scaffold for bioactivity.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of chemical probes and enzyme inhibitors for target identification and validation.
• Organic Synthesis Building Block: Employed in medicinal chemistry for the construction of complex heterocycles and for introducing the guanidine-like carboxamidine functionality.
• Material Science Research: Potential precursor for specialty polymers or ligands in catalytic systems due to its multifunctional groups.

Basic Information

Product Name	4-(Hydroxy)Piperidine-1-Carboxamidine
CAS No.	108001-76-9
Molecular Formula	C7H15N3O
Molecular Weight	157.22 g/mol
Synonyms	1-Carbamimidoyl-4-hydroxypiperidine; 4-Hydroxy-1-piperidinecarboxamidine; 4-Hydroxypiperidine-1-carboxamidine; 4-Piperidinol, 1-(aminoiminomethyl)-; 1-(Aminoiminomethyl)-4-piperidinol; 4-Hydroxy-N-amidinopiperidine-1-carboximidamide; 1-Piperidinecarboxamidine, 4-hydroxy-
EINECS	Contact for details

Quality Control

Our 4-(Hydroxy)Piperidine-1-Carboxamidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product quality and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.