Description

1-(4-(Trifluoromethyl)Benzyl)Piperazine is a high-value, functionalized piperazine derivative characterized by its trifluoromethylbenzyl moiety, which imparts unique physicochemical properties critical for advanced synthesis. This compound serves as a versatile and essential pharmaceutical intermediate and organic building block in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily utilized by research institutions and industrial manufacturers in the life sciences sector for creating novel compounds with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the trifluoromethyl group for improved efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme inhibition and receptor binding.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Item	Details
Product Name	1-(4-(Trifluoromethyl)Benzyl)Piperazine
CAS No.	107890-32-4
Molecular Formula	C12H15F3N2
Molecular Weight	244.26 g/mol
Synonyms	1-[(4-Trifluoromethyl)phenyl]methylpiperazine; 1-[(4-Trifluoromethyl)benzyl]piperazine; 4-(Trifluoromethyl)benzylpiperazine; α-(4-Trifluoromethylphenyl)-1-piperazinemethane; N-[(4-Trifluoromethyl)phenyl]methylpiperazine; 1-(4-Trifluoromethylbenzyl)piperazine; 1-(4-(Trifluoromethyl)benzyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(4-(Trifluoromethyl)Benzyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.