Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a critical chiral building block and intermediate for the development of novel pharmaceuticals and bioactive compounds. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing libraries of compounds in drug discovery programs to explore new biological activities.
• Process Chemistry & Scale-Up: Serves as a defined intermediate in the optimization and commercial-scale synthesis of target drug candidates.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce complex molecular architectures due to its fixed (7R-Cis) configuration.
• Biochemical Research: Potential use as a standard or probe in enzymatic studies or as a precursor for labeled compounds in metabolic research.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci)
CAS No.	107676-54-0
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	(7R-cis)-Hexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; 7-Hydroxyhexahydropyrrolo[1,2-a]pyrazine-1,4-dione, (7R-cis)-; Hexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazine-1,4-dione, (7R-cis)-; (7R)-Hexahydro-7-hydroxy-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-, (7R-cis)-; 1H-Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-7-hydroxy-, (7R-cis)-
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-7-Hydroxy-, (7R-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic characterization (NMR, IR, MS) are provided to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.