Description

9(R)-Hete is a specific stereoisomer of the hydroxyeicosatetraenoic acid (HETE) family, a class of bioactive lipid mediators derived from arachidonic acid. This compound matters as a key chiral reference standard and research chemical for studying the stereospecific biological activities of eicosanoids in various physiological and pathological processes. It is needed by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, biochemical pathway analysis, and as a critical component in analytical method development and validation.

Application

• Biochemical Research: Used as a high-purity reference standard in studies of eicosanoid signaling pathways, inflammation, and immune response mechanisms.
• Pharmaceutical Development: Serves as a critical intermediate or chiral building block in the synthesis of novel therapeutic agents targeting lipid mediator receptors.
• Analytical Chemistry: Essential for calibrating analytical instruments (e.g., HPLC, LC-MS) and developing validated methods for the quantification of HETEs in biological samples.
• Cell Biology & Pharmacology: Employed in in vitro and ex vivo assays to investigate the stereospecific effects of lipid mediators on cell function and receptor binding.
• Diagnostic Kit Manufacturing: Utilized in the production of diagnostic assays and kits designed to detect and measure specific eicosanoid levels for clinical research.

Basic Information

Product Name	9(R)-Hete
CAS No.	107656-14-4
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	(9R)-HETE; 9(R)-HETE; 9R-Hydroxy-5Z,7E,11Z,14Z-eicosatetraenoic Acid; (R)-9-Hydroxyeicosatetraenoic Acid; 9R-HETE; 9(R)-Hydroxyeicosatetraenoic Acid; 9R-Hydroxyeicosatetraenoic Acid; (9R)-Hydroxy-5Z,7E,11Z,14Z-eicosatetraenoic Acid
EINECS	Contact for details

Quality Control

Our 9(R)-Hete is produced under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for research chemicals, and specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (Optical Rotation)	[α]²⁰D: Specific range provided per COA
Assay (HPLC)	≥ 95% (Area Percent)
Purity (Chiral HPLC)	≥ 98% Enantiomeric Excess (e.e.)
Solubility	Soluble in ethanol, DMSO, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.