Description

1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-4-Methyl- (9Ci) is a specialized heterocyclic building block and acid chloride derivative of significant interest in advanced organic synthesis. Its core value lies in its high reactivity, serving as a key precursor for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), fine chemicals, and novel materials where the introduction of a functionalized quinoline moiety is required.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and fungicides that incorporate the quinoline scaffold for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, bioconjugation, or as a precursor for activity-based probes in biochemical research.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals used in various industrial and research applications.

Basic Information

Product Name	1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-4-Methyl- (9Ci)
CAS No.	106969-90-8
Molecular Formula	C11H10ClNO
Molecular Weight	207.66 g/mol
Synonyms	4-Methyl-3,4-dihydro-1(2H)-quinolinecarbonyl chloride; 4-Methyl-1,2,3,4-tetrahydroquinoline-1-carbonyl chloride; 1,2,3,4-Tetrahydro-4-methylquinoline-1-carbonyl chloride; 4-Methyl-3,4-dihydro-2H-quinoline-1-carbonyl chloride; Tetrahydro-4-methylquinoline-1-carbonyl chloride; 1-Carboxy-4-methyl-1,2,3,4-tetrahydroquinoline chloride; 4-Methyl-1-oxo-1,2,3,4-tetrahydroquinoline-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1(2H)-Quinolinecarbonyl Chloride, 3,4-Dihydro-4-Methyl- (9Ci) adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.