Description

(S)-2-Isobutyl-Piperazine CAS NO 106576-37-8 is a high-purity, chiral piperazine derivative characterized by its specific stereochemistry at the 2-position. This compound is a critical chiral building block and intermediate in the synthesis of advanced pharmaceutical active ingredients and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and receptor modulators.
• Asymmetric Catalyst Ligand: Used as a precursor for chiral ligands in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing novel chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic & R&D: A valuable reagent for medicinal chemistry research, process chemistry development, and exploring new synthetic methodologies.

Basic Information

Product Name	(S)-2-Isobutyl-Piperazine
CAS No.	106576-37-8
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(S)-2-(2-Methylpropyl)piperazine; (S)-2-Isobutylpiperazine; (S)-2-(Isobutyl)piperazine; (2S)-2-(2-Methylpropyl)piperazine; (S)-(-)-2-Isobutylpiperazine; L-2-Isobutylpiperazine; (S)-Piperazine, 2-(2-methylpropyl)-; 106576-37-8
EINECS	Contact for details

Quality Control

Our (S)-2-Isobutyl-Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.