Description

1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, cis- (9Ci) is a specialized, high-purity aldehyde derivative featuring a protected dioxolane ring system. This compound serves as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block for constructing stereogenic centers in natural products and specialty chemicals.
• Fine Chemical Production: Serves as a precursor in the manufacture of high-value agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: Used in methodological development and catalysis studies within organic chemistry laboratories.
• Ligand and Catalyst Development: Acts as a starting material for creating novel chiral ligands and organocatalysts.
• Material Science Research: Potential monomer or modifier in the development of specialized polymers with unique properties.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, cis- (9Ci)
CAS No.	106544-44-9
Molecular Formula	C9H16O3
Molecular Weight	172.22 g/mol
Synonyms	cis-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carboxaldehyde; (4S,5S)-2,2,4,5-Tetramethyl-1,3-dioxolane-4-carbaldehyde; 4-Formyl-2,2,4,5-tetramethyl-1,3-dioxolane (cis); Tetramethyl-dioxolane carboxaldehyde; Chiral dioxolane aldehyde; (cis)-4,5-Dimethyl-2,2-dimethyl-1,3-dioxolane-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 1,3-Dioxolane-4-Carboxaldehyde, 2,2,4,5-Tetramethyl-, cis- (9Ci) is produced under strict quality management protocols. Our products undergo rigorous quality testing including chiral purity analysis, identity confirmation, and impurity profiling to ensure compliance with exacting R&D and production standards. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.