Description

2,4-Dihydro-4-[(4-(4-Hydroxyphenyl)-1-Piperazinyl)Phenyl]-2-(1-Methylpropyl)-3H-1,2,4-Triazole-3-One is a high-purity, complex heterocyclic compound featuring a triazolone core linked to a hydroxyphenylpiperazine moiety. This specific molecular architecture makes it a valuable advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting central nervous system and receptor-specific pathways.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for developing compounds with potential biological activity, especially in neurological and psychiatric applications.
• Biochemical Tool Compound: Serves as a reference standard or probe in pharmacological studies to investigate specific receptor interactions and signaling pathways.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create more complex, high-value specialty chemicals for advanced research.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	2,4-Dihydro-4-[(4-(4-Hydroxyphenyl)-1-Piperazinyl)Phenyl]-2-(1-Methylpropyl)-3H-1,2,4-Triazole-3-One
CAS No.	106461-41-0
Molecular Formula	C22H27N5O2
Molecular Weight	393.48 g/mol
Synonyms	4-[4-(4-Hydroxyphenyl)piperazin-1-yl]phenyl-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; 2-(1-Methylpropyl)-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one; 106461-41-0; 1,2,4-Triazole-3-one, 2,4-dihydro-4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-; 4-(4-(4-Hydroxyphenyl)piperazin-1-yl)phenyl-2-(sec-butyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
EINECS	Contact for details

Quality Control

Our production of 2,4-Dihydro-4-[(4-(4-Hydroxyphenyl)-1-Piperazinyl)Phenyl]-2-(1-Methylpropyl)-3H-1,2,4-Triazole-3-One adheres to stringent quality protocols suitable for research-grade pharmaceutical intermediates. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.