Description

4-[(4-Methylpiperazin-1-Yl)Methyl]Benzoic Acid Dihydrochloride is a high-purity, pharmaceutically relevant organic salt primarily used as a key synthetic intermediate in active pharmaceutical ingredient (API) development. This compound is valued for its role in constructing complex molecular architectures, particularly in medicinal chemistry for drug discovery and process research. It is essential for R&D chemists and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable building blocks for novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies during drug discovery.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Synthesis: Utilized in the development of chemical probes, diagnostic agents, and targeted drug delivery systems.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and novel organic synthesis methodologies.

Basic Information

Product Name	4-[(4-Methylpiperazin-1-Yl)Methyl]Benzoic Acid Dihydrochloride
CAS No.	106261-49-8
Molecular Formula	C13H20N2O2 • 2HCl
Molecular Weight	313.23 g/mol (Free base: 244.31 g/mol)
Synonyms	Benzoic acid, 4-[(4-methyl-1-piperazinyl)methyl]-, dihydrochloride; 4-((4-Methylpiperazin-1-yl)methyl)benzoic acid dihydrochloride; 4-(4-Methylpiperazin-1-ylmethyl)benzoic acid hydrochloride (1:2); p-[(4-Methyl-1-piperazinyl)methyl]benzoic acid dihydrochloride; 106261-49-8; UNII-8JQ5607IO5; 8JQ5607IO5
EINECS	Contact for details

Quality Control

Our 4-[(4-Methylpiperazin-1-Yl)Methyl]Benzoic Acid Dihydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.