Description

1,2-Dipalmitoyl Glycero-3-Thiophosphate is a synthetic phospholipid derivative where a thiophosphate group replaces the typical phosphate, offering unique chemical reactivity and biological activity. This structural modification makes it a valuable intermediate for advanced research in lipidomics, membrane biophysics, and drug delivery systems. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for developing novel liposomal formulations and studying cell signaling pathways.

Application

• Lipidomics Research: A critical standard and building block for synthesizing and studying complex, sulfur-containing phospholipids and their role in cellular membranes.
• Drug Delivery Systems: Used as a functionalized lipid component in the design of advanced liposomal and nanoparticle carriers for targeted therapeutic delivery.
• Biochemical Probes: Serves as a substrate or inhibitor in enzymatic studies related to phospholipid metabolism and signal transduction pathways.
• Membrane Biophysics: Employed in model membrane systems (e.g., vesicles, bilayers) to investigate the effects of thiophosphate incorporation on membrane structure and dynamics.
• Pharmaceutical Intermediates: Acts as a key synthetic precursor for the development of novel bioactive compounds and potential active pharmaceutical ingredients (APIs).
• Specialty Surfactants: Potential use in formulating high-value, specialized surfactants for niche industrial or research applications.

Basic Information

Item	Details
Product Name	1,2-Dipalmitoyl Glycero-3-Thiophosphate
CAS No.	106249-23-4
Molecular Formula	C35H69O7PS
Molecular Weight	664.94 g/mol
Synonyms	1,2-Dihexadecanoyl-sn-glycero-3-thiophosphoric acid; DPP-thiophosphate; 1,2-Dipalmitoyl-sn-glycerol-3-thiophosphate; sn-Glycero-3-thiophosphoric acid 1,2-dipalmitate; Thiophosphatidic acid dipalmitoyl ester; Glycerol 1,2-dipalmitate 3-thiophosphate; PA(SH)-16:0/16:0; 3-Thiophosphoryl-1,2-dipalmitoyl-sn-glycerol
EINECS	Contact for details

Quality Control

Our 1,2-Dipalmitoyl Glycero-3-Thiophosphate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in chloroform, DCM; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.