Description

(-)-Rubifolide is a specific enantiomer of the naturally occurring sesquiterpene lactone rubifolide, identified by CAS No. 106231-29-2. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its unique stereochemistry and bioactive potential. It serves as a valuable chiral building block and reference standard for researchers in medicinal chemistry and natural product development.

Application

• Pharmaceutical Research & Development: Acts as a key chiral intermediate or reference standard in the synthesis of novel bioactive molecules and drug candidates.
• Medicinal Chemistry Studies: Used to investigate structure-activity relationships (SAR) and for biological screening against various therapeutic targets.
• Natural Product Synthesis: Serves as a sophisticated starting material or model compound for the total synthesis of complex sesquiterpene lactones.
• Analytical Reference Standard: Employed in HPLC, LC-MS, and NMR for method development, calibration, and the identification of related compounds in complex mixtures.
• Biochemical Research: Utilized in studies exploring enzyme interactions, metabolic pathways, and other biochemical mechanisms involving sesquiterpene frameworks.

Basic Information

Product Name	(-)-Rubifolide
CAS No.	106231-29-2
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	(3aR,4S,7S,7aR)-4,7-Dimethyl-3a,4,7,7a-tetrahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione; (-)-Rubifolide; L-Rubifolide; Rubifolide, (-)-; (3aR,4S,7S,7aR)-4,7-Dimethylhexahydro-4,7-epoxyisobenzofuran-1,3-dione
EINECS	Contact for details

Quality Control

Our (-)-Rubifolide is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material tailored to specific research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.