Description

3-Chloropyrazin-2-Ol is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive chloropyrazine core, which enables the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development and production of advanced herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Research & Development: Serves as a fundamental building block in medicinal chemistry for creating novel compound libraries and exploring new chemical spaces.
• Material Science: Potential use in the synthesis of organic ligands for catalysts or as a monomer for specialized polymers.
• Cross-Coupling Reactions: The chlorine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Nucleophilic Substitution: The reactive site allows for functionalization to introduce amines, alkoxides, and other nucleophiles, expanding molecular diversity.

Basic Information

Product Name	3-Chloropyrazin-2-Ol
CAS No.	105985-17-9
Molecular Formula	C4H3ClN2O
Molecular Weight	130.53 g/mol
Synonyms	2-Hydroxy-3-chloropyrazine; 3-Chloro-2-pyrazinol; 3-Chloro-2(1H)-pyrazinone; 3-Chloro-2-hydroxypyrazine; 3-Chloropyrazin-2(1H)-one; 2-Chloro-3-hydroxypyrazine; 3-Chloro-1H-pyrazin-2-one
EINECS	Contact for details

Quality Control

Our 3-Chloropyrazin-2-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.