Description

9-Hydroxyestrone-11-Nitrate is a chemically modified derivative of the natural estrogen metabolite estrone, featuring both a hydroxy and a nitrate ester functional group. This specific structural modification makes it a valuable synthetic intermediate and reference standard for advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel steroid-based compounds and the study of metabolic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel steroid derivatives with potential therapeutic applications.
• Biochemical Research: Used as a reference standard in metabolic studies to understand the pathways and effects of estrogen derivatives.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for method development, calibration, and quality control in analytical laboratories.
• Academic Research: Utilized in university and institutional labs for investigating steroid chemistry, nitration reactions, and structure-activity relationships (SAR).

Basic Information

Product Name	9-Hydroxyestrone-11-Nitrate
CAS No.	105801-89-6
Molecular Formula	C18H21NO5
Molecular Weight	331.37 g/mol
Synonyms	11-Nitrooxy-9-hydroxyestra-1,3,5(10)-trien-17-one; 9-Hydroxy-11-nitrooxyestrone; Estrone, 9-hydroxy-11-nitrate; 9,11-Dioxygenated Estrone Derivative; 9-Hydroxyestrone 11-Nitrate Ester
EINECS	Contact for details

Quality Control

Our 9-Hydroxyestrone-11-Nitrate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.