Description

4-(Piperazin-1-Yl)-1H-Indazole is a high-purity, nitrogen-containing heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique piperazine-indazole scaffold makes it a valuable intermediate for developing novel pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study biological pathways and protein function.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents and pesticides.
• Academic & Contract Research: Utilized in university and CRO laboratories for fundamental organic synthesis and methodological research.

Basic Information

Item	Details
Product Name	4-(Piperazin-1-Yl)-1H-Indazole
CAS No.	105684-53-5
Molecular Formula	C11H14N4
Molecular Weight	202.26 g/mol
Synonyms	1H-Indazole, 4-(1-piperazinyl)-; 4-(1-Piperazinyl)-1H-indazole; 4-Piperazin-1-yl-1H-indazole; 4-(Piperazin-1-yl)-1H-indazole; 4-(Piperazin-1-yl)indazole; 1H-Indazole, 4-(piperazinyl)-; 4-Piperazinylindazole; 4-(Piperazin-1-yl)-1H-indazole (CAS 105684-53-5)
EINECS	Contact for details

Quality Control

Our 4-(Piperazin-1-Yl)-1H-Indazole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ISO 9001 quality management principles, and our analytical methods, including HPLC, NMR, and MS, are validated to provide reliable data for our customers' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.