Description

5-[4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]Benzyl]-2,4-Thiazolidinedione is a high-purity pharmaceutical intermediate and research chemical of significant importance in medicinal chemistry. This compound is a thiazolidinedione derivative, a class known for its role in modulating peroxisome proliferator-activated receptors (PPARs). It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in the development of metabolic disorder therapeutics and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced drug candidates targeting type 2 diabetes and insulin resistance.
• PPAR Research: Critical reference standard and active compound in biochemical research focused on Peroxisome Proliferator-Activated Receptor (PPAR) gamma agonism and related metabolic pathways.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new thiazolidinedione analogs.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for producing specialized, high-value chemical entities.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	5-[4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]Benzyl]-2,4-Thiazolidinedione
CAS No.	105390-47-4
Molecular Formula	C19H20N2O3S
Molecular Weight	356.44 g/mol
Synonyms	5-{4-[2-(5-Ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 5-(4-(2-(5-Ethyl-2-pyridinyl)ethoxy)benzyl)-2,4-thiazolidinedione; 105390-47-4; Thiazolidinedione derivative (PPAR-γ ligand); 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
EINECS	Contact for details

Quality Control

Our 5-[4-[2-(5-Ethyl-2-Pyridyl)Ethoxy]Benzyl]-2,4-Thiazolidinedione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.