Description

1,2-Propanediol,3-[5-(Hydroxymethyl)Pyrazinyl]-,(S)-(9Ci) is a high-purity, chiral chemical intermediate of significant interest in advanced organic synthesis. Its unique structure, featuring both a pyrazine ring and a propanediol chain, makes it a valuable building block for creating complex, biologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemicals. We supply this material with a focus on consistent quality and reliable global availability to support critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurologic and metabolic disorders.
• Ligand and Catalyst Synthesis: Used to construct sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Serves as a linker or spacer molecule in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Research: Employed as a building block in the discovery of new, more selective herbicides and fungicides.
• Fine Chemical Synthesis: Integral to the multi-step synthesis of complex flavors, fragrances, and specialty chemicals requiring high stereochemical purity.
• Academic & Discovery Chemistry: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs at universities and corporate labs.

Basic Information

Item	Detail
Product Name	1,2-Propanediol,3-[5-(Hydroxymethyl)Pyrazinyl]-,(S)-(9Ci)
CAS No.	104696-23-3
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	(S)-3-[5-(Hydroxymethyl)pyrazin-2-yl]propane-1,2-diol; (2S)-3-(5-Hydroxymethyl-2-pyrazinyl)-1,2-propanediol; 2-Pyrazinemethanol, β,2-dihydroxy-4-(S)-1-methyl-2-hydroxyethyl)-; A potential metabolite of certain pharmaceutical compounds; Chiral pyrazine-diol derivative.
EINECS	Contact for details

Quality Control

Every batch of our 1,2-Propanediol,3-[5-(Hydroxymethyl)Pyrazinyl]-,(S)-(9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting critical parameters such as chiral purity, chemical purity, and identity confirmation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.