Description

2,6-Dichloro-4-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)-1-((Trimethylsilyl)Oxy)Ethyl)Benzeneamine is a sophisticated, high-purity synthetic intermediate featuring a complex molecular architecture. This compound is of significant value in advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecules with specific biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or cardiovascular diseases.
• Research Chemical: Used in academic and industrial laboratories for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of API manufacturing routes.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, high-value fine chemicals for clients in the life sciences sector.

Basic Information

Product Name	2,6-Dichloro-4-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)-1-((Trimethylsilyl)Oxy)Ethyl)Benzeneamine
CAS No.	104672-12-0
Molecular Formula	C25H35Cl2N3O4Si
Molecular Weight	540.56 g/mol
Synonyms	4-Amino-2,6-dichloro-α-[(trimethylsilyl)oxy]-4'-(2,3,4-trimethoxyphenyl)-1-piperazinepropiophenone; 1-[4-Amino-3,5-dichlorophenyl]-2-[4-[(2,3,4-trimethoxyphenyl)methyl]-1-piperazinyl]-1-[(trimethylsilyl)oxy]ethane; TMS-protected amino ketone piperazine derivative; CAS 104672-12-0; 2,6-Dichloro-4-[2-[4-[(2,3,4-trimethoxyphenyl)methyl]-1-piperazinyl]-1-(trimethylsilyloxy)ethyl]aniline
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-4-(2-(4-((2,3,4-Trimethoxyphenyl)Methyl)-1-Piperazinyl)-1-((Trimethylsilyl)Oxy)Ethyl)Benzeneamine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.