Description

1,2,3-Propanetriol,1-(5-Methylpyrazinyl)-,[R-(R*,S*)]-(9Ci) is a specialized chiral glycerol derivative containing a methylpyrazinyl substituent, serving as a high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of advanced, targeted pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Asymmetric Synthesis: Serves as a chiral synthon or auxiliary in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Ligand & Catalyst Development: Precursor for creating novel ligands and organocatalysts used in homogeneous catalysis and transition metal complexes.
• Fine Chemical Manufacturing: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Institutional Research: Used in chemical biology and medicinal chemistry research programs to study structure-activity relationships (SAR).

Basic Information

Product Name	1,2,3-Propanetriol,1-(5-Methylpyrazinyl)-,[R-(R*,S*)]-(9Ci)
CAS No.	104670-27-1
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	(2R,3S)-1-(5-Methylpyrazin-2-yl)propane-1,2,3-triol; 1-(5-Methyl-2-pyrazinyl)-1,2,3-propanetriol, (2R,3S)-; (2R,3S)-1-(5-Methylpyrazinyl)glycerol; Glycerol, 1-(5-methyl-2-pyrazinyl)-, (2R,3S)-; Chiral Methylpyrazinyl Glycerol Derivative; (R*,S*)-1-(5-Methylpyrazin-2-yl)propane-1,2,3-triol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. For this chiral intermediate, quality is assured through comprehensive analytical methods including chiral HPLC to confirm enantiomeric excess (ee) and standard identity/purity tests. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for purity, chiral purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere such as nitrogen or argon after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.