Description

1-(Bis[4-(Trifluoromethyl)Phenyl]Methyl)Piperazine is a specialized fluorinated piperazine derivative, a high-value intermediate designed for advanced chemical synthesis. Its molecular architecture, featuring multiple trifluoromethylphenyl groups, provides unique steric and electronic properties critical for developing compounds with enhanced stability and bioactivity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors seeking to incorporate sophisticated fluorinated motifs into new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research where fluorinated compounds are prized for their metabolic stability and membrane permeability.
• Agrochemical Development: Used in creating advanced pesticides and herbicides, where the trifluoromethyl groups can significantly improve lipophilicity, environmental stability, and target binding affinity.
• Ligand and Catalyst Synthesis: Serves as a precursor for complex ligands in catalysis and as a scaffold for materials science applications requiring specific molecular recognition properties.
• Organic Electronics Research: Investigated as a potential component in the development of organic semiconductors and charge-transport materials due to its electron-deficient aromatic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to fine chemical companies and CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex fluorinated intermediates.

Basic Information

Product Name	1-(Bis[4-(Trifluoromethyl)Phenyl]Methyl)Piperazine
CAS No.	104523-09-3
Molecular Formula	C20H18F6N2
Molecular Weight	400.36 g/mol
Synonyms	1-([Bis(4-(trifluoromethyl)phenyl)]methyl)piperazine; 1-[[Bis[4-(trifluoromethyl)phenyl]methyl]piperazine; α,α-Bis[4-(trifluoromethyl)phenyl]-1-piperazinemethane; 1-(Di(4-(trifluoromethyl)phenyl)methyl)piperazine; Piperazine, 1-[[bis[4-(trifluoromethyl)phenyl]methyl]-; 1-(Bis(4-trifluoromethylphenyl)methyl)piperazine
EINECS	Contact for details

Quality Control

We maintain a stringent quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Our standard offering typically meets a purity specification of ≥97% (by HPLC), with rigorous control of related substances and residual solvents. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.