Description

Ethyl 2-Piperazin-1-Yl-Thiazole-4-Carboxylate is a high-purity synthetic organic compound featuring a piperazine-substituted thiazole core. This versatile heterocyclic building block is critical for research and development in advanced pharmaceutical synthesis, particularly in the creation of novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, antimicrobial agents, and kinase inhibitors.
• Agrochemical Research: Serves as a building block for developing novel pesticides, herbicides, and fungicides due to its bioactive thiazole-piperazine scaffold.
• Chemical Biology & Proteomics: Used in the design and synthesis of chemical probes and molecular tools for studying biological pathways and protein interactions.
• Material Science Research: Potential precursor for synthesizing specialized ligands, catalysts, or functional polymers with specific electronic or binding properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	Ethyl 2-Piperazin-1-Yl-Thiazole-4-Carboxylate
CAS No.	104481-24-5
Molecular Formula	C10H15N3O2S
Molecular Weight	241.31 g/mol
Synonyms	Ethyl 2-(piperazin-1-yl)thiazole-4-carboxylate; 2-(1-Piperazinyl)-4-thiazolecarboxylic acid ethyl ester; 4-Thiazolecarboxylic acid, 2-(1-piperazinyl)-, ethyl ester; Ethyl 2-piperazinyl-4-thiazolecarboxylate; 104481-24-5; Ethyl 2-(piperazin-1-yl)-1,3-thiazole-4-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Piperazin-1-Yl-Thiazole-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.