Description

1-Piperazinepropanamide, n-(2-Nitrophenyl)-4-(2-Pyridinyl)-, Dihydrochloride is a high-purity, non-peptidic chemical intermediate of significant interest in advanced pharmaceutical research and development. Its molecular structure, featuring a piperazine core linked to nitrophenyl and pyridinyl groups, makes it a valuable building block for creating novel bioactive compounds. This material is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Chemical Biology Probe Development: Used to create tool compounds for studying enzyme function and protein-protein interactions in biological pathways.
• Library Synthesis for High-Throughput Screening (HTS): Employed in the construction of diverse compound libraries to identify new lead molecules with therapeutic potential.
• Medicinal Chemistry Research: Acts as a scaffold for structure-activity relationship (SAR) studies to optimize the potency and selectivity of new chemical entities.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-Piperazinepropanamide, n-(2-Nitrophenyl)-4-(2-Pyridinyl)-, Dihydrochloride
CAS No.	104373-63-9
Molecular Formula	C18H21N5O3 • 2HCl
Molecular Weight	436.31 g/mol (for dihydrochloride salt)
Synonyms	N-(2-Nitrophenyl)-4-(2-pyridinyl)-1-piperazinepropanamide dihydrochloride; 1-Piperazinepropanamide, N-(2-nitrophenyl)-4-(2-pyridinyl)-, dihydrochloride; UNII-8J6N9A3K4F; 8J6N9A3K4F; N-(2-Nitrophenyl)-4-(pyridin-2-yl)piperazine-1-carboxamide dihydrochloride; 4-(2-Pyridinyl)-N-(2-nitrophenyl)-1-piperazinepropanamide dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Piperazinepropanamide, n-(2-Nitrophenyl)-4-(2-Pyridinyl)-, Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.