Description

n-Methyl Fenoldopam Hydrochloride is a chemically modified derivative of fenoldopam, a selective dopamine D1 receptor agonist. This compound is of significant interest in pharmaceutical research and development, particularly for studying cardiovascular pharmacology and receptor-ligand interactions. It serves as a critical intermediate or reference standard for researchers and manufacturers in the pharmaceutical and fine chemical sectors, enabling the synthesis and analysis of novel therapeutic agents.

Application

• Pharmaceutical Research Intermediate: A key building block in the synthesis of novel dopamine receptor-targeting compounds for cardiovascular and renal research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical substances.
• Biochemical Studies: Employed in in-vitro studies to investigate the structure-activity relationships (SAR) of dopamine D1 receptor agonists.
• Process Development: Serves as a critical material for scaling up and optimizing synthetic routes in active pharmaceutical ingredient (API) manufacturing.
• Metabolite Studies: Utilized as a standard in pharmacokinetic and metabolic profiling studies of fenoldopam and its analogs.

Basic Information

Product Name	n-Methyl Fenoldopam Hydrochloride
CAS No.	104113-95-3
Molecular Formula	C17H20ClNO3 • HCl
Molecular Weight	358.26 g/mol
Synonyms	N-Methylfenoldopam Hydrochloride; 6-Chloro-7,8-dihydroxy-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine Hydrochloride; SKF-82526-J Hydrochloride; Fenoldopam Methyl Ester Hydrochloride; (6-Chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-methyl-1H-3-benzazepine) Hydrochloride; 1-Methyl Fenoldopam HCl
EINECS	Contact for details

Quality Control

Our n-Methyl Fenoldopam Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.