Description

11(α)-Methoxysaikosaponin F is a specific, high-purity saponin derivative isolated from Bupleurum species. This compound is valued for its role as a critical reference standard and active pharmaceutical ingredient (API) intermediate in advanced research and development. It is primarily utilized by pharmaceutical, biotechnology, and nutraceutical companies focused on metabolic, inflammatory, and hepatic therapeutic areas. Our supply ensures consistent quality and reliable availability for your critical projects.

Application

• Pharmaceutical Reference Standard: For the qualitative and quantitative analysis (HPLC, LC-MS) of saikosaponin-containing formulations and raw materials.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key building block in the synthesis of novel therapeutic agents.
• Biomedical Research: Used in in vitro and in vivo studies to investigate mechanisms related to inflammation, liver protection, and metabolic regulation.
• Natural Product Standardization: Essential for standardizing herbal extracts, particularly those derived from Bupleurum (Chai Hu), to ensure potency and batch-to-batch consistency.
• Nutraceutical Development: Incorporated into high-end supplement formulations where validated bioactive markers are required.
• Academic Research: Supplied to universities and research institutes for pharmacological and phytochemical studies.

Basic Information

Item	Detail
Product Name	11(α)-Methoxysaikosaponin F
CAS No.	104109-37-7
Molecular Formula	C48H78O18
Molecular Weight	943.13 g/mol
Synonyms	11α-Methoxysaikosaponin F; Saikosaponin F 11-methyl ether; 3-O-β-D-Glucopyranosyl(1→3)-β-D-fucopyranosyl saikogenin F 11-methyl ether; (3β,4α,16β)-3-[[O-β-D-Glucopyranosyl-(1→3)-O-β-D-fucopyranosyl]oxy]-16,23:16,30-diepoxy-11-methoxy-4,4,8-trimethyl-21,24-cyclo-9,19-cyclolanost-25(26)-en-28-oic acid β-D-glucopyranosyl ester
EINECS	Contact for details

Quality Control

Every batch of 11(α)-Methoxysaikosaponin F is manufactured and analyzed under strict quality management systems. We employ advanced chromatographic techniques (HPLC, LC-MS) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with each shipment, supporting compliance with GMP and ICH guidelines for pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤2.0%
Residual Solvents (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.