Description

(S)-tert-Butyl Piperazine-3-Carboxylate CAS NO 104069-74-1 is a high-purity chiral piperazine derivative, serving as a critical building block in modern organic synthesis. Its enantiomeric purity and protected carboxylate group make it an invaluable intermediate for constructing complex molecules with defined stereochemistry. This compound is primarily sought after by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Building block for developing enantiomerically pure pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Preparation: Precursor for synthesizing chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics & Bioactive Molecules: Core structure for designing protease inhibitors, receptor modulators, and other biologically active compounds.
• Custom Synthesis & Contract Manufacturing: Essential starting material for custom synthesis projects requiring high stereochemical fidelity.
• Academic & Industrial R&D: Used in research laboratories for methodological development and exploring new chemical spaces.

Basic Information

Product Name	(S)-tert-Butyl Piperazine-3-Carboxylate
CAS No.	104069-74-1
Molecular Formula	C9H18N2O2
Molecular Weight	186.25 g/mol
Synonyms	(S)-1-Boc-3-piperazinecarboxylic acid; (S)-1-tert-Butoxycarbonylpiperazine-3-carboxylic acid; (S)-3-(tert-Butoxycarbonyl)piperazine-1-carboxylic acid; (S)-N-Boc-piperazine-3-carboxylic acid; (S)-Piperazine-3-carboxylic acid, 1-(1,1-dimethylethyl) ester; (3S)-1-(tert-Butoxycarbonyl)piperazine-3-carboxylic acid; 1-Boc-3-piperazinecarboxylic acid, (S)-; tert-Butyl (S)-piperazine-3-carboxylate
EINECS	Contact for details

Quality Control

Our (S)-tert-Butyl Piperazine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure it meets the high-purity standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.