Description

13-Hydroxygermacrone is a bioactive sesquiterpenoid compound, a key derivative of germacrone. This compound matters for its role as a crucial intermediate and reference standard in advanced pharmaceutical and phytochemical research. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries for developing new therapeutic agents and high-purity botanical extracts.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in anti-inflammatory and anticancer research.
• Analytical Reference Standard: Used as a high-purity standard in HPLC, LC-MS, and GC-MS for the quality control and quantification of germacrone and related compounds in complex matrices.
• Natural Product Research: Essential for studying the biosynthesis, metabolism, and pharmacological activities of sesquiterpenoids derived from traditional medicinal plants like Curcuma species.
• Cosmetic & Skincare Actives: Investigated for potential application in topical formulations targeting skin inflammation and oxidative stress due to its bioactive profile.
• Nutraceutical Development: Employed in the development and standardization of advanced herbal extracts intended for dietary supplements.

Basic Information

Product Name	13-Hydroxygermacrone
CAS No.	103994-29-2
Molecular Formula	C15H22O2
Molecular Weight	234.33 g/mol
Synonyms	13-Hydroxygermacra-1(10),4,7(11)-trien-8-one; Germacrone, 13-hydroxy-; 1(10),4,7(11)-Germacratrien-8-one, 13-hydroxy-; (1R,4S,7S,10S)-4-Hydroxy-4,11,11-trimethyl-8-methylenebicyclo[8.1.0]undec-5-en-2-one
EINECS	Contact for details

Quality Control

Our 13-Hydroxygermacrone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods for identity confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. For long-term storage, keep the material in a freezer at -20°C. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.