Description

3-Tyr-Octreotide is a synthetic peptide analog of somatostatin, specifically modified at the tyrosine residue. This compound is a critical intermediate and reference standard in the development and quality control of peptide-based pharmaceuticals. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors focused on endocrinology, oncology, and diagnostic imaging. The product is supplied to meet the stringent purity and consistency requirements of advanced therapeutic development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of octreotide and related therapeutic peptides.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of somatostatin analogs.
• Biomedical Research: Employed in preclinical studies to investigate receptor binding, pharmacokinetics, and the mechanisms of somatostatin receptors (SSTRs).
• Radiopharmaceutical Precursor: Acts as a precursor for the development of radiolabeled compounds used in diagnostic imaging and targeted radiotherapy.
• Process Development: Utilized in scaling up and optimizing manufacturing processes for peptide active pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Tyr-Octreotide
CAS No.	103667-46-5
Molecular Formula	C₄₉H₆₆N₁₀O₁₀S₂
Molecular Weight	1019.2 g/mol
Synonyms	3-Tyrosine-Octreotide; Tyr³-Octreotide; D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-ol (cyclic 2-7 disulfide); SMS 201-995 Tyr³ analog; Somatostatin analog Tyr³; Octreotide Tyr³ derivative; (3-Tyr)-Octreotide
EINECS	Contact for details

Quality Control

Our 3-Tyr-Octreotide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.