Description

1-Piperazinebutanoic Acid, 4-[(Phenylmethoxy)Carbonyl]-, Ethyl Ester is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile intermediate with a protected amine group for the controlled construction of complex molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in medicinal chemistry for creating libraries of bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents, including herbicides and fungicides, where its piperazine core contributes to biological activity.
• Peptidomimetics & Bioconjugation: Serves as a crucial spacer or linker unit in the design of peptidomimetics and for bioconjugation strategies in drug delivery systems.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects requiring specific, protected heterocyclic intermediates.
• Ligand & Catalyst Development: Acts as a precursor for ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for exploratory chemistry in academic institutions and corporate R&D laboratories focused on heterocyclic chemistry.

Basic Information

Product Name	1-Piperazinebutanoic Acid, 4-[(Phenylmethoxy)Carbonyl]-, Ethyl Ester
CAS No.	103433-37-0
Molecular Formula	C18H26N2O4
Molecular Weight	334.41 g/mol
Synonyms	Ethyl 4-[(benzyloxy)carbonyl]piperazine-1-butanoate; 1-Carbobenzoxypiperazine-4-butyric Acid Ethyl Ester; 4-(N-Cbz)piperazine-1-butanoic Acid Ethyl Ester; 1-(3-Ethoxycarbonylpropyl)-4-carbobenzoxypiperazine; N-Cbz-piperazine-1-butyric Acid Ethyl Ester; 4-(Benzyloxycarbonyl)-1-piperazinebutanoic Acid Ethyl Ester; Piperazine-1-butyric acid, 4-[(phenylmethoxy)carbonyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our 1-Piperazinebutanoic Acid, 4-[(Phenylmethoxy)Carbonyl]-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.