Description

1-Thiohexadecyl-2-Ethyl-Glycero-3-Phosphocholine is a specialized synthetic phospholipid derivative, a key building block in advanced lipid-based research and formulation. This compound is valued for its unique structure, which combines a long-chain thioether linkage with a phosphocholine head group, offering distinct chemical and physical properties compared to conventional phospholipids. It is primarily utilized by researchers and product developers in the pharmaceutical and biotechnology sectors for applications such as liposome and nanoparticle engineering, membrane studies, and drug delivery system development.

Application

• As a critical raw material for the synthesis of novel liposomal drug carriers and lipid nanoparticles (LNPs).
• In the research and development of membrane mimetics and model systems for studying cell membrane interactions and dynamics.
• As a functional component in the formulation of non-viral gene delivery vectors and transfection reagents.
• For the creation of targeted therapeutic systems, where its structure can be leveraged for surface modification and ligand attachment.
• In the development of diagnostic imaging agents and contrast media that utilize lipid-based encapsulation.
• As a specialty surfactant or emulsifier in high-value cosmetic and dermatological formulations requiring specific membrane-fluidizing properties.

Basic Information

Item	Detail
Product Name	1-Thiohexadecyl-2-Ethyl-Glycero-3-Phosphocholine
CAS No.	103304-64-9
Molecular Formula	C26H56NO5PS
Molecular Weight	525.76 g/mol
Synonyms	1-Hexadecylthio-2-ethyl-glycero-3-phosphocholine; 2-Ethyl-1-hexadecylthio-sn-glycero-3-phosphocholine; S-Hexadecyl-2-ethyl-sn-glycero-3-phosphocholine; Thioether Phospholipid; Phosphatidylcholine analogue; Lipid 103304-64-9; S-Palmitoyl-2-ethyl-sn-glycero-3-phosphocholine (common name variant)
EINECS	Contact for details

Quality Control

Our 1-Thiohexadecyl-2-Ethyl-Glycero-3-Phosphocholine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for research and pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is -20°C or below. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.