Description

12(S)-Hpepe is a high-purity, stereospecific eicosanoid derivative, a key intermediate in the synthesis of specialized pro-resolving mediators (SPMs) and other bioactive lipid compounds. Its precise stereochemistry at the 12(S) position is critical for biological activity and research reproducibility. This compound is essential for pharmaceutical R&D, academic research in inflammation and immunology, and the development of advanced analytical standards.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of pro-resolving lipid mediators like Lipoxins and Resolvins.
• Biochemical Research: Used as a reference standard and precursor in studies of eicosanoid pathways, inflammation resolution, and cell signaling.
• Analytical Standard: Serves as a high-purity calibrant for LC-MS, HPLC, and GC-MS analysis in metabolomics and lipidomics.
• Drug Discovery: Employed in screening assays and as a starting material for developing novel anti-inflammatory therapeutics.
• Academic & Institutional Research: Supports fundamental research in biochemistry, pharmacology, and molecular biology.

Basic Information

Product Name	12(S)-Hpepe
CAS No.	103239-14-1
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	12(S)-HpEPE; 12(S)-Hydroperoxyeicosapentaenoic acid; (12S)-HPEPE; 12(S)-HpEPE; 12S-Hydroperoxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid; 12(S)-HPETE (often used interchangeably for the eicosapentaenoic acid derivative); 12(S)-Hydroperoxyeicosapentaenoate; 12S-HpEPE
EINECS	Contact for details

Quality Control

Every batch of 12(S)-Hpepe is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) detailing purity by HPLC, stereochemical purity, and impurity profiles. Our quality systems support research and development requiring GMP-grade intermediates and certified reference materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95%
Stereochemical Purity (Chiral HPLC)	≥ 98% 12(S) isomer
Related Substances (HPLC)	Total impurities ≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.