Description

Hepoxilin A4 CAS NO 103188-13-2 is a specialized eicosanoid metabolite derived from arachidonic acid, playing a significant role in cellular signaling pathways. This compound is valued for its biological activity as a mediator in inflammatory and immune responses. It is primarily sought by researchers and developers in the pharmaceutical and life science sectors for use in biochemical research, drug discovery, and as a reference standard for analytical studies.

Application

• Biochemical Research: Used as a critical reference standard and tool compound for studying eicosanoid metabolism and signaling pathways.
• Pharmaceutical R&D: Serves as a key intermediate or active metabolite in the development of novel anti-inflammatory and immunomodulatory therapeutics.
• Cell Biology Studies: Employed to investigate the role of hepoxilins in cellular processes such as calcium mobilization, insulin secretion, and neutrophil migration.
• Analytical Chemistry: Utilized as a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques.
• Enzymology: Acts as a substrate or product in assays for enzymes like 12-lipoxygenase and hepoxilin synthase.

Basic Information

Product Name	Hepoxilin A4
CAS No.	103188-13-2
Molecular Formula	C20H32O4
Molecular Weight	336.47 g/mol
Synonyms	HXA4; (8R,9S,10S,11Z,14Z)-8,9,10-Trihydroxyicosa-11,14-dienoic acid; 8(R),9(S),10(S)-Trihydroxy-11(Z),14(Z)-eicosadienoic acid; 8,9,10-Trihydroxy-11,14-eicosadienoic acid; Hepoxilin A4 methyl ester (related derivative); 12-Lipoxygenase metabolite of arachidonic acid
EINECS	Contact for details

Quality Control

Our Hepoxilin A4 is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in ethanol, DMSO; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.