Description

1-[3-[(1,2-Dihydro-2-Methyl-1-Oxopyrrolo[1,2-A]Pyrazin)-3-Yl]Propyl]Guanidine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs). Research and development teams in the pharmaceutical and biotechnology sectors need this material for creating next-generation therapeutic agents, particularly in areas requiring sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders or oncological pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• API Synthesis: Integral in multi-step synthetic routes for producing final active pharmaceutical ingredients that incorporate the pyrrolopyrazine-guanidine pharmacophore.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research due to its reactive guanidine moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials and commercial APIs.

Basic Information

Product Name	1-[3-[(1,2-Dihydro-2-Methyl-1-Oxopyrrolo[1,2-A]Pyrazin)-3-Yl]Propyl]Guanidine
CAS No.	102482-94-0
Molecular Formula	C13H18N6O
Molecular Weight	274.32 g/mol
Synonyms	3-[3-(Aminomethyl)propyl]-2-methyl-1H-pyrrolo[1,2-a]pyrazin-1-one; 1-[3-(2-Methyl-1-oxo-1,2-dihydropyrrolo[1,2-a]pyrazin-3-yl)propyl]guanidine; Guanidine, N-[3-(2-methyl-1-oxo-1H-pyrrolo[1,2-a]pyrazin-3-yl)propyl]-; Pyrrolo[1,2-a]pyrazin-1(2H)-one, 3-[3-(aminomethyl)propyl]-2-methyl-; 102482-94-0; (Compound with pyrrolopyrazine core and guanidine side chain)
EINECS	Contact for details

Quality Control

Our 1-[3-[(1,2-Dihydro-2-Methyl-1-Oxopyrrolo[1,2-A]Pyrazin)-3-Yl]Propyl]Guanidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided, and we can support regulatory filings with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.