Description

4-(4-Chlorophenylsulfanyl)Piperidine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial interest. This compound matters for its role as a key synthon in the development of active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and therapeutic agent research.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new pharmacophores.
• Chemical Synthesis: Serves as a versatile precursor for constructing complex piperidine and sulfanyl-containing molecular architectures.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents and pesticides.
• Material Science: Can be utilized in the development of specialty polymers and advanced organic materials.
• Contract Research & Manufacturing (CRAM): Supplied to organizations requiring reliable, high-quality custom synthesis starting materials.

Basic Information

Product Name	4-(4-Chlorophenylsulfanyl)Piperidine Hydrochloride
CAS No.	101798-64-5
Molecular Formula	C11H14ClNS•HCl
Molecular Weight	264.61 g/mol
Synonyms	4-[(4-Chlorophenyl)thio]piperidine hydrochloride; 4-(p-Chlorophenylthio)piperidine HCl; 1-(4-Chlorophenylsulfanyl)piperidin-4-yl hydrochloride; Piperidine, 4-[(4-chlorophenyl)thio]-, hydrochloride; 4-(4-Chlorobenzenesulfanyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-(4-Chlorophenylsulfanyl)Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.