Description

(2-Methyl-3-Nitro-Phenyl)-Acetyl Chloride CAS NO 101566-00-1 is a specialized organic intermediate featuring a reactive acid chloride functional group. This compound is critical for the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key building block. It is primarily sought after by research institutions and industrial manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a substituted phenylacetyl moiety.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and pesticides, where its nitro and acyl chloride groups enable further functionalization.
• Fine Chemical Production: Serves as a versatile building block for creating complex organic compounds used in dyes, pigments, and specialty polymers.
• Research & Development: Essential for medicinal chemistry and process chemistry research in both academic and industrial laboratories for exploring new synthetic pathways.
• Peptide Mimetic Chemistry: The acetyl chloride group can be used to acylate amines, making it useful for creating peptide-like structures and amide bonds in combinatorial chemistry.

Basic Information

Product Name	(2-Methyl-3-Nitro-Phenyl)-Acetyl Chloride
CAS No.	101566-00-1
Molecular Formula	C9H8ClNO3
Molecular Weight	213.62 g/mol
Synonyms	2-Methyl-3-nitrobenzeneacetyl chloride; 2-Methyl-3-nitrophenylacetyl chloride; (2-Methyl-3-nitrophenyl)acetyl chloride; 3-Nitro-2-methylphenylacetyl chloride; α-Chloro-2-methyl-3-nitroacetophenone; 2-(2-Methyl-3-nitrophenyl)acetyl chloride; NSC 405124
EINECS	Contact for details

Quality Control

Our (2-Methyl-3-Nitro-Phenyl)-Acetyl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from moisture, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.