Description

β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate is a high-purity chiral salt form of a key pharmaceutical intermediate. This compound is critical for ensuring the stereochemical integrity and bioavailability of active pharmaceutical ingredients (APIs) in advanced drug formulations. It is primarily required by pharmaceutical R&D laboratories and manufacturing facilities specializing in enantiomerically pure therapeutics, such as cardiovascular and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used as a resolving agent or chiral auxiliary in stereoselective chemical reactions.
• Cardiovascular Drug Development: Key precursor in the manufacture of specific β-blockers and related cardiovascular therapeutics.
• Central Nervous System (CNS) Agents: Employed in the research and production of drugs targeting neurological pathways.
• Process Chemistry & Scale-Up: Serves as a standard for process optimization and validation in kilo-lab and pilot plant operations.
• Analytical Reference Standard: Used as a high-purity standard for HPLC, LC-MS, and chiral analysis in quality control laboratories.

Basic Information

Product Name	β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate
CAS No.	100208-43-3
Molecular Formula	C13H21NO6
Molecular Weight	287.31 g/mol
Synonyms	(1R,2S)-Ephydroxytartrate; (R,R)-Pseudoephedrine Hydrogen Tartrate; L-Pseudoephedrine Bitartrate; α-(1-Hydroxymethyl)ethyl]benzylammonium (2R,3R)-Hydrogen Tartrate; Pseudoephedrine (R,R)-Hydrogen Tartrate Salt; 1-Phenyl-2-methylamino-1-propanol (R,R)-Hydrogen Tartrate; (1R,2S)-(-)-Ephedrine Hydrogentartrate (less common); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, assay, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.