Description

7-[3-(4-Benzoyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is a high-purity xanthine derivative with a complex piperazine-based side chain, representing a key advanced pharmaceutical intermediate. This compound matters for its role in the synthesis of specialized active pharmaceutical ingredients (APIs) targeting neurological and cardiovascular pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel adenosine receptor antagonists and phosphodiesterase (PDE) inhibitors.
• Neurological Research: Used in preclinical studies for developing compounds targeting neurodegenerative diseases and cognitive disorders.
• Cardiovascular Drug Development: Applied in research for creating potential therapeutics for heart failure and hypertension.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Biochemical Assay Development: Employed in the development of in vitro screening assays for drug discovery platforms.

Basic Information

Product Name	7-[3-(4-Benzoyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione
CAS No.	19972-09-9
Molecular Formula	C21H26N6O4
Molecular Weight	426.47 g/mol
Synonyms	1,3-Dimethyl-7-[3-(4-benzoyl-1-piperazinyl)-2-hydroxypropyl]xanthine; 7-[3-(4-Benzoylpiperazin-1-yl)-2-hydroxypropyl]-1,3-dimethylpurine-2,6-dione; 1,3-Dimethyl-7-[2-hydroxy-3-(4-benzoyl-1-piperazinyl)propyl]xanthine; BPPX; Benzoylpiperazinyl hydroxypropyl theophylline derivative; Contact for details
EINECS	Contact for details

Quality Control

Our 7-[3-(4-Benzoyl-1-Piperazinyl)-2-Hydroxypropyl]-1,3-Dimethyl-7H-Purine-2,6(1H,3H)-Dione is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.