Description

Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Methyl-, (3R-Trans)- (8Ci,9Ci) is a high-purity, stereochemically defined heterocyclic compound of significant interest in advanced organic synthesis. This molecule serves as a sophisticated chiral building block and key intermediate for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals and flavors & fragrances.
• Academic and R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.
• Peptidomimetic Scaffolds: Its fused bicyclic structure makes it suitable for designing peptidomimetics and protease inhibitors.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Methyl-, (3R-Trans)- (8Ci,9Ci)
CAS No.	19943-28-3
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(3R,3aR)-Hexahydro-3-methylpyrrolo[1,2-a]pyrazine-1,4-dione; (3R-trans)-Hexahydro-3-methylpyrrolo[1,2-a]pyrazine-1,4-dione; 3-Methylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; (3R,3aR)-3-Methylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione; L-Proline, N-(1-oxopropyl)-, lactam; A chiral bicyclic lactam; Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-methyl-, (3R,3aR)-
EINECS	Contact for details

Quality Control

Every batch of our Pyrrolo[1,2-A]Pyrazine-1,4-Dione, Hexahydro-3-Methyl-, (3R-Trans)- is manufactured under a strict quality management system. We guarantee high chiral purity and chemical integrity through advanced analytical techniques including HPLC, GC, and chiral chromatography. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with each shipment to ensure compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.