Description

(3As,6E,8S,10E,11Ar)-3A,4,5,8,9,11A-Hexahydro-8-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity. This compound is valued as a key intermediate and research chemical in the development of novel pharmaceuticals and agrochemicals. It is primarily sought by R&D laboratories and fine chemical manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for synthesis and biological screening programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting anti-inflammatory or anti-cancer pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its natural product-inspired structure.
• Biochemical Research: Employed as a standard or probe in studies investigating sesquiterpene biosynthesis, enzyme inhibition, or structure-activity relationships (SAR).
• Fine Chemical Synthesis: Acts as a starting material or advanced intermediate for the custom synthesis of complex, high-value specialty chemicals.
• Natural Product Analog Development: Used to create synthetic analogs of natural sesquiterpene lactones for enhanced stability, bioavailability, or potency.

Basic Information

Product Name	(3As,6E,8S,10E,11Ar)-3A,4,5,8,9,11A-Hexahydro-8-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One
CAS No.	19888-11-0
Molecular Formula	C15H20O3
Molecular Weight	248.32 g/mol
Synonyms	8-Hydroxy-6,10-dimethyl-3-methylidene-4,5,8,9,11,11a-hexahydro-3aH-cyclodeca[b]furan-2-one; 3-Methylene-8-hydroxy-6,10-dimethyl-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one; Parthenolide analog; Sesquiterpene lactone derivative; Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-8-hydroxy-6,10-dimethyl-3-methylene-, (3aR,6E,8S,10E,11aR)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a cGMP-compliant quality management system to ensure traceability and consistency for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.