Description

Chlofenamic Acid CAS NO 19865-61-3 is a halogenated derivative of fenamic acid, belonging to the class of non-steroidal anti-inflammatory drugs (NSAIDs). This compound is valued for its potent pharmacological activity, primarily as a cyclooxygenase (COX) inhibitor, making it a critical intermediate in pharmaceutical research and development. It is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries focused on developing new anti-inflammatory and analgesic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Biochemical Research: Used as a reference standard and a selective COX-2 inhibitor in pharmacological and enzymatic studies to investigate inflammation pathways.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Academic Research: Employed in universities and research institutions for studying structure-activity relationships (SAR) of fenamate derivatives.
• Veterinary Medicine: Investigated for potential applications in developing anti-inflammatory treatments for animals.

Basic Information

Product Name	Chlofenamic Acid
CAS No.	19865-61-3
Molecular Formula	C14H10ClNO2
Molecular Weight	259.69 g/mol
Synonyms	2-[(3-Chloro-2-methylphenyl)amino]benzoic acid; N-(3-Chloro-2-methylphenyl)anthranilic acid; Clofenamic Acid; Chlofenamate; NSC 113029; Compound 19865-61-3; 3'-Chloro-2-methylfenamic Acid
EINECS	243-349-3

Quality Control

Our Chlofenamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.