Description

5,8-Dimethyl-1,2,4-Triazolo[4,3-A]Pyrazine-3-Thiol is a heterocyclic organic compound that serves as a versatile and high-value synthetic intermediate. Its fused triazolopyrazine core with a thiol functional group makes it a critical building block for the development of advanced materials and active pharmaceutical ingredients (APIs). This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its privileged heterocyclic scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the triazolopyrazine structure can contribute to novel modes of action.
• Ligand in Catalysis: The thiol and nitrogen-rich structure allows it to act as a ligand for metal complexes in catalytic applications.
• Material Science: Serves as a building block for organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Utilized in research to create molecular probes for studying enzyme function or protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	5,8-Dimethyl-1,2,4-Triazolo[4,3-A]Pyrazine-3-Thiol
CAS No.	19854-99-0
Molecular Formula	C7H8N4S
Molecular Weight	180.23 g/mol
Synonyms	5,8-Dimethyl-[1,2,4]triazolo[4,3-a]pyrazine-3-thiol; 3-Mercapto-5,8-dimethyl-[1,2,4]triazolo[4,3-a]pyrazine; 5,8-Dimethyl-1,2,4-triazolo[4,3-a]pyrazine-3-thione; 1,2,4-Triazolo[4,3-a]pyrazine-3-thiol, 5,8-dimethyl-; 19854-99-0; DTZPT
EINECS	Contact for details

Quality Control

Our 5,8-Dimethyl-1,2,4-Triazolo[4,3-A]Pyrazine-3-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.