Description

(R)-5-Hydroxy-Piperidin-2-One is a chiral piperidinone derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and high-purity chiral building block, enabling the construction of complex molecules with precise stereochemistry. Pharmaceutical R&D and fine chemical manufacturers need it for developing active pharmaceutical ingredients (APIs), particularly in neurological and metabolic research areas.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential CNS drugs and enzyme inhibitors.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Peptidomimetics & Bioactive Molecule Construction: Serves as a constrained scaffold for designing peptide analogs and other bioactive compounds.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Agrochemical Research: Potential intermediate in the development of chiral active ingredients for crop protection.
• Academic & Contract Research: A valuable reagent for methodological development in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	(R)-5-Hydroxy-Piperidin-2-One
CAS No.	19365-07-2
Molecular Formula	C5H9NO2
Molecular Weight	115.13 g/mol
Synonyms	(R)-5-Hydroxy-2-piperidinone; (R)-5-Hydroxypiperidin-2-one; (R)-5-Hydroxy-δ-valerolactam; (R)-5-Hydroxy-2-piperidone; (3R)-3-Hydroxypiperidin-2-one; (R)-5-Hydroxy-2-oxopiperidine; (R)-5-Hydroxypiperidinone; 5-Hydroxy-2-piperidinone, (R)-
EINECS	Contact for details

Quality Control

Our (R)-5-Hydroxy-Piperidin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiles via validated methods such as HPLC and GC. Certificates of Analysis (COA) are available upon request for every batch, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.