Description

Hexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione CAS NO 19179-12-5 is a heterocyclic organic compound belonging to the diketopiperazine class. This versatile building block is of significant interest in pharmaceutical research and fine chemical synthesis due to its rigid, bicyclic scaffold. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a core scaffold for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Peptidomimetics Research: Used as a constrained dipeptide mimic (diketopiperazine) to study peptide conformation and develop metabolically stable bioactive compounds.
• Agrochemical Synthesis: Acts as a precursor in the development of novel herbicides, fungicides, and insecticides with enhanced biological activity.
• Chemical Biology Probe: Utilized in academic and industrial research to create molecular probes for studying enzyme function and protein-protein interactions.
• Material Science Precursor: Potential starting material for the synthesis of specialty polymers and functional organic materials with specific thermal or optical properties.

Basic Information

Item	Detail
Product Name	Hexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione
CAS No.	19179-12-5
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	1,4-Diazabicyclo[4.3.0]nonane-2,5-dione; 2,5-Diketopiperazine, Hexahydro-1H-pyrrolo[1,2-a]pyrazine-1,4-dione; Cyclo(Gly-Pro); Glycylproline diketopiperazine; Cyclo(glycyl-L-prolyl); L-Glycyl-L-proline anhydride; GP-DKP; c(Gly-Pro)
EINECS	Contact for details

Quality Control

Our Hexahydropyrrolo[1,2-A]Pyrazine-1,4-Dione is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.