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1-Stearoyl-2-Arachidonylphosphatidylcholine CAS NO 18892-74-5


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CAS No.:18892-74-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Stearoyl-2-Arachidonylphosphatidylcholine is a defined, high-purity phospholipid species, a critical component for advanced biochemical and pharmaceutical research. This compound is essential for studying membrane biophysics, lipid signaling pathways, and the role of specific phospholipids in cellular function. It is particularly valuable for researchers and manufacturers in lipidomics, drug delivery systems (liposomes), and as a standard in analytical chemistry.

Application

  • Lipidomics Research & Biomarker Discovery: Used as a pure standard for the identification and quantification of phospholipids in complex biological samples via mass spectrometry.
  • Liposome & Drug Delivery System Formulation: A key structural lipid for creating defined, stable liposomal carriers for targeted drug and gene delivery.
  • Biochemical & Cell Biology Studies: Essential for investigating the specific roles of phosphatidylcholine species in cell membrane dynamics, signal transduction (e.g., via arachidonic acid release), and apoptosis.
  • Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and assay development in pharmaceutical laboratories.
  • Model Membrane Systems: Used to create synthetic lipid bilayers (e.g., vesicles, supported lipid bilayers) with precise composition for biophysical studies.
  • Nutritional & Cosmetic Research: Investigated for its potential role in specialized nutraceutical formulations and advanced cosmetic delivery systems.

Basic Information

Product Name 1-Stearoyl-2-Arachidonylphosphatidylcholine
CAS No. 18892-74-5
Molecular Formula C46H84NO8P
Molecular Weight 810.14 g/mol
Synonyms SAPC; 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine; PC(18:0/20:4); Phosphatidylcholine(18:0/20:4(5Z,8Z,11Z,14Z)); 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine; (2R)-2-[(5Z,8Z,11Z,14Z)-Icosatetraenoyloxy]-3-(octadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate; L-α-1-Stearoyl-2-arachidonyl Phosphatidylcholine
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Quality Control

Our 1-Stearoyl-2-Arachidonylphosphatidylcholine is manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, MS, and NMR to confirm identity, purity, and fatty acid composition. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms
Assay (HPLC) ≥ 95%
Fatty Acid Composition (GC) Conforms to structure (C18:0 at sn-1, C20:4 at sn-2)
Solubility Soluble in chloroform, ethanol; slightly soluble in hexane

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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