Description

3,3'-Thiodipropionyl Dichloride is a versatile and highly reactive sulfur-containing diacid chloride. This compound is a critical building block in organic synthesis, valued for its ability to introduce a thiodipropionate linkage, which can impart properties like flexibility, thermal stability, and antioxidant activity to final products. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, polymer, and specialty chemical industries for applications ranging from polymer modification to the synthesis of functional additives.

Application

• Pharmaceutical Intermediates: Key synthon for producing prodrugs, linkers for antibody-drug conjugates (ADCs), and active pharmaceutical ingredients (APIs) requiring a sulfur-based bridge.
• Polymer Chemistry: Used as a monomer or cross-linking agent in the synthesis of polyesters, polyamides, and other specialty polymers to enhance properties like chain flexibility and thermal resistance.
• Lubricant & Fuel Additives: Serves as a precursor for antioxidants and anti-wear additives, helping to improve the oxidative stability and performance of industrial lubricants and fuels.
• Surface Modification Agents: Employed to functionalize surfaces or materials (e.g., silica, polymers) by introducing thioether groups for improved adhesion or specific chemical reactivity.
• Chemical Synthesis: A versatile reagent for acylations and the preparation of esters, amides, and other derivatives in fine chemical and agrochemical research.
• Cosmetic Ingredients: Intermediate in the production of certain specialty esters used in personal care formulations.

Basic Information

Product Name	3,3'-Thiodipropionyl Dichloride
CAS No.	18733-39-6
Molecular Formula	C6H8Cl2O2S
Molecular Weight	215.10 g/mol
Synonyms	Thiodipropionyl Dichloride; 3,3'-Thiobis(propanoyl chloride); Bis(3-chloro-3-oxopropyl) sulfide; Propanoic acid, 3,3'-thiobis-, dichloride; β,β'-Thiodipropionyl chloride; 3,3'-Dithiodipropionyl dichloride (related); Sulfonyldipropionyl dichloride
EINECS	242-542-9

Quality Control

Every batch of 3,3'-Thiodipropionyl Dichloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards and provide comprehensive analytical data. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee consistency and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic and highly volatile nature, it should be kept under an inert atmosphere (e.g., nitrogen or argon) and away from moisture. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Acid Chloride Content	≥ 99.0% (by titration)
Water Content (KF)	≤ 0.5%
Related Impurities (HPLC)	≤ 1.0% (any single impurity)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.