Description

1,2-Dimyristoyl-Rac-Glycero-3-Phosphocholine is a synthetic, racemic phospholipid belonging to the phosphatidylcholine (PC) class, characterized by two identical myristoyl (C14:0) fatty acid chains. This compound is a critical building block for creating model lipid membranes, enabling research into membrane biophysics, protein-lipid interactions, and cellular delivery mechanisms. It is essential for scientists and formulators in the pharmaceutical, biotechnology, and advanced materials sectors who require high-purity lipids for liposome preparation, drug delivery systems, and biomimetic studies.

Application

• Liposome & Nanoparticle Formulation: A key component for creating unilamellar and multilamellar vesicles used as drug delivery carriers for active pharmaceutical ingredients (APIs).
• Biomembrane & Model System Research: Used to construct supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) for studying membrane fluidity, permeability, and protein incorporation.
• Cell Culture & Transfection Reagents: Serves as a raw material in the development of non-viral transfection agents and serum supplements for specialized cell culture applications.
• Cosmetic & Dermal Delivery Systems: Incorporated into niosomes and other vesicular systems for the encapsulation and enhanced skin penetration of cosmetic actives.
• Diagnostic Reagent Development: Utilized in the formulation of lipid-based reagents for diagnostic assays and imaging contrast agents.
• Biophysical & Analytical Standards: Acts as a high-purity standard in analytical techniques like mass spectrometry and chromatography for lipidomics research.

Basic Information

Product Name	1,2-Dimyristoyl-Rac-Glycero-3-Phosphocholine
CAS No.	18656-38-7
Molecular Formula	C36H72NO8P
Molecular Weight	677.93 g/mol
Synonyms	DMPC; 1,2-Dimyristoyl-sn-glycero-3-phosphocholine (rac); 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine; Phosphatidylcholine (14:0/14:0); 3-sn-Phosphatidylcholine, 1,2-dimyristoyl-; rac-1,2-Dimyristoylphosphatidylcholine; Myristoyl Phosphatidyl Choline; PC(14:0/14:0)
EINECS	242-461-6

Quality Control

Our 1,2-Dimyristoyl-Rac-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and formulation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical characteristics are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and exposure to air.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 10 ppm
Solvent Residues (GC)	Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.