Description

(R)-Piperidine-2-Carboxylic Acid Methyl Ester Hydrochloride is a high-purity chiral building block essential for the synthesis of complex pharmaceutical molecules. Its defined stereochemistry provides a critical advantage in creating enantiomerically pure active pharmaceutical ingredients (APIs) and advanced intermediates. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various APIs, particularly those targeting neurological and cardiovascular disorders.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, and auxiliaries used in stereoselective chemical transformations.
• Peptidomimetics Research: Used in the design and development of novel peptide-like compounds with enhanced metabolic stability and bioavailability.
• Agrochemical Development: Employed in the research phase for creating enantiomerically pure herbicides and pesticides.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and process development in fine chemical synthesis.

Basic Information

Product Name	(R)-Piperidine-2-Carboxylic Acid Methyl Ester Hydrochloride
CAS No.	18650-38-9
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(R)-Methyl Pipecolate Hydrochloride; (R)-Methyl Pipecolinate Hydrochloride; (R)-Methyl 2-Piperidinecarboxylate Hydrochloride; (R)-Pipecolinic Acid Methyl Ester Hydrochloride; (R)-2-Methoxycarbonylpiperidine Hydrochloride; (R)-2-Carbomethoxypiperidine Hydrochloride; (R)-Piperidine-2-carboxylic acid, methyl ester, hydrochloride; (R)-Methyl L-Pipecolate Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-Piperidine-2-Carboxylic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.