Description

1,2-Dihydro-α-Santonin is a hydrogenated derivative of the sesquiterpene lactone α-santonin, a compound historically significant in medicinal chemistry. This refined intermediate is valued for its modified chemical structure, which offers enhanced stability and specific reactivity profiles for advanced synthetic applications. It is primarily utilized by research institutions and pharmaceutical development teams engaged in the synthesis of novel therapeutic agents and the study of structure-activity relationships within the sesquiterpene lactone class.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the research and development of new drug candidates, particularly in anti-inflammatory and antiparasitic therapeutic areas.
• Organic Synthesis Research: Used as a model compound or starting material in academic and industrial laboratories for studying hydrogenation reactions and lactone chemistry.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, GC).
• Medicinal Chemistry Studies: Facilitates exploration into the bioactivity and metabolic pathways of santonin derivatives for potential pharmacological applications.
• Fine Chemical Production: Acts as a precursor in the multi-step synthesis of complex, high-value specialty chemicals and advanced intermediates.

Basic Information

Product Name	1,2-Dihydro-α-Santonin
CAS No.	18409-93-3
Molecular Formula	C₁₅H₂₀O₃
Molecular Weight	248.32 g/mol
Synonyms	1,2-Dihydro-α-santonin; Dihydro-α-santonin; (3S,3aS,5aS,9bS)-3,5a,9-Trimethyl-3a,4,5,5a,9,9b-hexahydronaphtho[1,2-b]furan-2,8(3H,7H)-dione; α-Santonin, 1,2-dihydro-; Santonin, dihydro-; 1,2-Dihydrosantonin
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-α-Santonin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.