Description

2-Chloro-6-Methylpyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic reactivity of the chlorine atom and the methyl group, enabling precise molecular construction for complex target molecules. This intermediate is essential for research and production facilities in the pharmaceutical and agrochemical sectors, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of various drug candidates, including kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and plant growth regulators.
• Ligand Precursor: Serves as a starting material for the synthesis of specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research and production of liquid crystals, organic semiconductors, and other electronic chemicals.
• Cross-Coupling Reactions: An effective substrate in Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl structures.
• Nucleophilic Substitution: The chloro group is readily displaced by various nucleophiles, facilitating the introduction of amines, alkoxides, and other functionalities.

Basic Information

Product Name	2-Chloro-6-Methylpyridine
CAS No.	18368-63-3
Molecular Formula	C6H6ClN
Molecular Weight	127.57 g/mol
Synonyms	2-Chloro-6-picoline; 6-Methyl-2-chloropyridine; 2-Chloro-6-methylpyridine; 2-Chloro-6-picoline; 2-Chloro-6-methyl-pyridine; 2-Cl-6-MePy
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methylpyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.