Description

1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine (DMPC) is a synthetic, saturated phospholipid that serves as a fundamental building block for creating stable, well-defined lipid membranes. Its consistent chain length and high purity make it an essential material for researchers and formulators requiring precise control over bilayer properties and interactions. This phospholipid is critical for applications in advanced drug delivery systems, biophysical research, and the development of diagnostic assays.

Application

• Liposome & Nanoparticle Formulation: A primary component for creating stable, unilamellar vesicles used in drug delivery for encapsulating therapeutic agents.
• Membrane Biophysics Research: Used to create model lipid bilayers (e.g., supported lipid bilayers, black lipid membranes) for studying membrane protein function, permeability, and fusion mechanisms.
• Biomimetic Coatings: Employed to create biocompatible surfaces on sensors, implants, and diagnostic devices to reduce non-specific binding and improve performance.
• Cell Culture & Organoid Development: Acts as a lipid supplement in serum-free media formulations to support specialized cell growth and membrane integrity.
• Diagnostic Reagent Preparation: Used in the manufacture of control reagents, calibrators, and assay components that require defined lipid environments.
• Crystallization of Membrane Proteins: Provides a lipidic cubic phase or detergent-lipid mixtures to facilitate the structural determination of integral membrane proteins.

Basic Information

Product Name	1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine
CAS No.	18194-24-6
Molecular Formula	C36H72NO8P
Molecular Weight	677.93 g/mol
Synonyms	DMPC; 1,2-Ditetradecanoyl-sn-glycero-3-phosphocholine; Phosphatidylcholine, 1,2-dimyristoyl-; Dimyristoylphosphatidylcholine; L-α-Dimyristoylphosphatidylcholine; 14:0 PC; 1,2-Dimyristoylphosphatidylcholine; PC(14:0/14:0)
EINECS	242-071-1

Quality Control

Our 1,2-Dimyristoyl-Sn-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and lipid profile analysis, to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and specific impurities are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. This material is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Total Phospholipid)
Phase Transition Temperature (Tm)	Approx. 23-24°C
Solubility	Soluble in chloroform, methanol, ethanol; insoluble in water
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.