Description

[10E,12E,R,(-)]-9-Hydroxy-10,12-Octadecadienoic Acid is a specific stereoisomer of a conjugated hydroxy fatty acid, a class of compounds with significant biological activity. This high-purity compound is valued for its role as a key intermediate in advanced organic synthesis and biochemical research. It is primarily sought by researchers and manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries for developing novel bioactive molecules and studying lipid signaling pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block for the synthesis of prostaglandin analogs and other bioactive lipid mediators.
• Biochemical Research: Used as a reference standard and probe in studies of lipoxygenase pathways, inflammation, and cell signaling mechanisms.
• Nutraceutical Development: Investigated for potential applications in functional food ingredients due to its structural similarity to conjugated linoleic acid (CLA) derivatives.
• Organic Synthesis: Employed in stereoselective synthesis to create complex natural products and specialty chemicals with defined configurations.
• Cosmeceutical Research: Explored for potential topical applications in skincare formulations targeting specific biological pathways.

Basic Information

Product Name	[10E,12E,R,(-)]-9-Hydroxy-10,12-Octadecadienoic Acid
CAS No.	18104-44-4
Molecular Formula	C₁₈H₃₂O₃
Molecular Weight	296.45 g/mol
Synonyms	(9R)-9-Hydroxy-10E,12E-octadecadienoic acid; (-)-9-Hydroxy-10-trans,12-trans-octadecadienoic acid; 9R-HODE; 9(R)-HODE; (R)-(-)-9-HODE; 9-Hydroxy-10,12-octadecadienoic acid (R isomer); Conjugated linoleic acid hydroxy derivative
EINECS	Contact for details

Quality Control

Our [10E,12E,R,(-)]-9-Hydroxy-10,12-Octadecadienoic Acid is produced under stringent quality management systems. Each batch is characterized and tested to ensure high stereochemical purity and chemical identity. Comprehensive analytical methods including HPLC, GC-MS, and NMR are employed. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation. Allow the container to reach room temperature in a desiccator before opening to prevent moisture condensation. Store away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.