Description

(20S)-5β-Pregnane-3α,20-Diol Bis(Heptafluorobutyrate) is a high-purity, fluorinated steroid derivative of significant interest in advanced research and analytical chemistry. This compound serves as a critical analytical standard and a versatile synthetic intermediate for developing novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of diagnostic reagents who require precise and reliable reference materials.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of steroid metabolites and related compounds in method development and validation.
• Metabolite Research: Acts as a key intermediate or analog in metabolic pathway studies and the synthesis of labeled internal standards for mass spectrometry.
• Diagnostic Reagent Synthesis: Employed in the development of chemical reagents and conjugates for clinical diagnostic assays, particularly in hormone testing.
• Organic Synthesis Building Block: Serves as a specialized precursor for the synthesis of more complex steroid-based molecules with modified pharmacological properties.
• Biochemical Research: Utilized in studies investigating steroid hormone action, receptor binding, and enzyme inhibition mechanisms.

Basic Information

Product Name	(20S)-5β-Pregnane-3α,20-Diol Bis(Heptafluorobutyrate)
CAS No.	18072-44-1
Molecular Formula	C31H36F14O4
Molecular Weight	762.60 g/mol
Synonyms	5β-Pregnane-3α,20α-diol 3,20-bis(heptafluorobutyrate); 3α,20α-Dihydroxy-5β-pregnane 3,20-bis(2,2,3,3,4,4,4-heptafluorobutyrate); 20S-5β-Pregnane-3α,20-diol Diheptafluorobutyrate; Pregnane-3α,20-diol Bis(HFB); HFB Derivative of 5β-Pregnane-3α,20α-diol; Steroid HFB Ester; Heptafluorobutyryl Derivative of Pregnanediol.
EINECS	Contact for details

Quality Control

Every batch of (20S)-5β-Pregnane-3α,20-Diol Bis(Heptafluorobutyrate) is manufactured and tested under strict quality management systems. We employ advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its nature, the product should be kept away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.